Description
Solubility Information
Dihexa dissolves well in DMSO at a concentration of 1mg/ml.Adding 1ml of pure water may cause the solution to become cloudy.Applying ultrasonic treatment for 2 seconds typically clears the solution.
Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, or its developmental code name PNB-0408,
is an oligopeptide drug derived from ..
The molecular formula of Dihexa is C27H44N4O5, with a molar mass of
504.672 g·mol−1.
Dihexa consists of two hydrophobic amino acids—Tyr-Ile—with the full sequence as follows:
Hexanoyl-Tyr-Ile-Ahx-NH2.
Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, or its developmental code name PNB-0408,
is an oligopeptide drug derived from angiotensin IV. It binds with high affinity to hepatocyte growth factor (HGF)
and interacts with its receptor, c-Met.
The molecular formula of Dihexa is C27H44N4O5, with a molar mass of
504.672 g·mol−1.
Dihexa consists of two hydrophobic amino acids—Tyr-Ile—with the full sequence as follows:
Hexanoyl-Tyr-Ile-Ahx-NH2.Solubility InformationImportant: Due to its hydrophobic nature, Dihexa does not dissolve in pure water and must be mixed with a suitable solvent such as DMSO. This is essential for proper reconstitution.Based on laboratory testing and published research:Dihexa dissolves well in DMSO at a concentration of 1mg/ml.Adding 1ml of pure water may cause the solution to become cloudy.Applying ultrasonic treatment for 2 seconds typically clears the solution.This solubility profile influences the format in which Dihexa is supplied for research. Researchers intending to work with the lyophilised version should ensure access to DMSO or a similar solvent for proper handling.Storage GuidelinesStore the lyophilised peptide at -20°C. Once reconstituted, use it immediately or store it at 2–8°C for a short duration. Avoid repeated freeze-thaw cycles.Disclaimer: This product is intended for laboratory research use only. It is not approved for human or veterinary use.IdentificationMolecular Weight (g/mol)504.66 g/molPeptide SequenceN-hexanoic-Tyr-Ile-(6)aminohexanoic amideCAS Number1401708-83-5Physical and Chemical PropertiesMolecular FormulaC27H44N4O5AppearanceWhite to off-white lyophilised powderMelting PointNot applicable (decomposes before melting)Research Use and SafetyCautionHandle using appropriate PPE and in compliance with relevant laboratory safety standards.Intended UseFor laboratory research use only. Not for human or veterinary use.Hazard ClassificationNot classified as hazardous under GHS for research quantitiesStorage, Handling and StabilityStorage Temperature, Opened-20 °C, minimise freeze-thaw cyclesStorage Temperature, Unopened-20 °C recommended for long-term storageShelf Life2 years unopened under recommended conditionsReconstitution StabilityStable for up to 28 days at 2-8 °C in aqueous solution under sterile conditionsPrepared in accordance with UK REACH and UK CLP — 16 sections — Version 1.0Safety Data SheetFull 16-section UK Safety Data Sheet covering hazard identification, first-aid, handling and storage, exposure controls, physical and chemical properties, toxicology, ecology, transport and regulatory information. Issued by UK Peptides for research use only.Download PDFView full SDS onlineClassification: Not classified (UK CLP) — Transport: Not regulated (ADR / IMDG / IATA) — UK REACH SVHC: Not listed
